REGULATOR

Pronunție (USA): (GB):

Traducere în limba română

regulator substantiv

1. reglor, reglementator.

2. (tehn.) regulator, moderator, egalizator, compensator.

3. cronometru.

Exemple de propoziții și/sau fraze:

Viral Oncogene E1A encodes E1A Protein, a regulator of early viral gene transcription.

(Oncogene E1A, NCI Thesaurus)

Apoptosis regulator BAX (192 aa, ~21 kDa) is encoded by the human BAX gene.

(Apoptosis Regulator BAX, NCI Thesaurus)

Further experiments revealed that NASH-induced scarring depends on TGF-beta, a broad immune system regulator and target for experimental NASH therapies, and IL-13, a type 2 molecule produced by various immune cells, including eosinophils.

(NIH study sheds light on immune responses driving obesity-induced liver disease, National Institutes of Health)

The major regulator of blood pressure homeostasis is the renin-angiotensin system.

(Angiotensin-converting Enzyme 2 Pathway, NCI Thesaurus/BIOCARTA)

HIF-1alpha, normally activated in response to hypoxia-induced stress, is a key transcription regulator of a large number of genes important in cellular adaptation to low-oxygen conditions, including angiogenesis, cell proliferation, apoptosis, and cell invasion.

(Anti-HIF-1alpha LNA Antisense Oligonucleotide EZN-2968, NCI Thesaurus)

GRP78, the endoplasmic reticulum (ER) chaperone and unfolded protein response (UPR) regulator, is overexpressed on the surface of a variety of cancer cell types; its expression is associated with increased tumor cell survival and proliferation, as well as angiogenesis and resistance to chemotherapy.

(Anti-GRP78 Monoclonal Antibody PAT-SM6, NCI Thesaurus)

A single transcriptional regulator initially associated with the activation of the T-cells (NFATc4) has been shown to link genetic and environmental causes of one class of congenital heart disorders, birth defects involving valve and septum formation.

(NFAT Pathway, NCI Thesaurus/BIOCARTA)

As integral components of the late G1 restriction point, the Rb gene product and p16 are negative regulators of the cell cycle; ovarian cancer cells and non-small cell lung cancer cells may be defective in the Rb/p16 pathway.

(Oncolytic Ad5-Delta 24RGD, NCI Thesaurus)

The protein MDM2, a negative regulator of p53 activity, is overexpressed in many cancer cell types; the tumor suppressor p53 is mutated or deleted in about 50% of all cancers but active in the other 50%.

(Nutlin-3a, NCI Thesaurus)

TE-AR MAI PUTEA INTERESA