DYNAMICS

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Traducere în limba română

dynamics substantiv pl. (folosit ca sg.)

1. (fiz.) dinamică.

2. forţe motrice, impulsuri, stimulente.

Exemple de propoziții și/sau fraze:

The disruption in microtubule dynamics may eventually inhibit cell division and may reduce cellular growth.

(Cevipabulin Fumarate, NCI Thesaurus)

Noscapine binds to tubulin and alters its conformation, resulting in a disruption of the dynamics of microtubule assembly (by increasing the time that microtubules spend idle in a paused state) and subsequently, the inhibition of mitosis and tumor cell death.

(Noscapine Hydrochloride, NCI Thesaurus)

The monoclonal antibody moiety of anti-mesothelin antibody-drug conjugate BAY 94-9343 targets and binds to the tumor associated antigen mesothelin; upon internalization, the DM4 moiety binds to tubulin and disrupts microtubule assembly/disassembly dynamics, resulting in inhibition of cell division and cell growth of mesothelin-expressing tumor cells.

(Anti-mesothelin Antibody-Drug Conjugate BAY 94-9343, NCI Thesaurus)

A confirmation of intermediate black holes' existence, or lack of, will have profound implications for our understanding of the formation of supermassive black holes and the dynamics of the galaxies that host them, said Pedro Marronetti, a program director in NSF's Division of Physics.

(Observing 'black hole symphony' using gravitational wave astronomy, National Science Foundation)

The ATP-dependent Eg5 kinesin-related motor protein (also known as KIF11 or kinesin spindle protein-5) is a plus-end directed kinesin motor protein involved in the regulation of spindle dynamics, including assembly and maintenance, during mitosis.

(Eg5 Kinesin-Related Motor Protein Inhibitor ARQ 621, NCI Thesaurus)

Upon antibody/antigen binding and internalization, the immunoconjugate releases DM4, which binds to tubulin and disrupts microtubule assembly/disassembly dynamics, resulting in inhibition of cell division and cell growth of CA6-expressing tumor cells.

(Anti-CA6-DM4 Immunoconjugate SAR566658, NCI Thesaurus)

The monoclonal antibody moiety of DM4-conjugated anti-Cripto monoclonal antibody BIIB015 binds to the tumor associated antigen (TAA) Cripto; upon internalization, the DM4 moiety binds to tubulin and disrupts microtubule assembly/disassembly dynamics, resulting in inhibition of cell division and cell growth of Cripto-expressing tumor cells.

(DM4-Conjugated Anti-Cripto Monoclonal Antibody BIIB015, NCI Thesaurus)

The ATP-dependent Eg5 kinesin-related motor protein (also known as KIF11 or kinesin spindle protein-5) is a plus-end directed kinesin motor protein essential for the regulation of spindle dynamics, including assembly and maintenance, during mitosis.

(Eg5 Kinesin-Related Motor Protein Inhibitor 4SC-205, NCI Thesaurus)

Anti-myeloma cell surface antigen immunoconjugate BT-062 binds to an unspecified cell surface antigen highly expressed on myeloma cells; upon internalization the DM4 moiety is released, binding to tubulin and disrupting microtubule assembly/disassembly dynamics, which may result in the inhibition of cell division and cell growth of myeloma tumor cells.

(Anti-Myeloma Monoclonal Antibody-DM4 Immunoconjugate BT-062, NCI Thesaurus)

Integrin-targeted immunoconjugate IMGN388 binds to tumor cell surface integrins; upon internalization, the DM4 moiety is released from the immunoconjugate, binding to tubulin and disrupting microtubule assembly/disassembly dynamics, which may result in inhibition of cell division and cell growth of integrin-expressing tumor cells.

(Anti-Integrin Monoclonal Antibody-DM4 Immunoconjugate IMGN388, NCI Thesaurus)

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